An individual is having an inversion in heterozygous condition. The regions on normal chromosome are marked as A, B, C, D, E, F, G while the chromosome having inversion has the regions as a, b, e, d, c, f, g. The diagram given below shows pairing of these two homologous chromosomes during meiosis and the site of a crossing over is indicated:

The following statements are given to describe the inversion and the consequence of crossing over shown in the above diagram:

A. This is a paracentric inversion

B. This will generate a dicentric and an acentric chromosome following separation of chromosomes after crossing over

C. This will generate two recombinant chromosomes with deletion and other parental chrmosome following separation of chromosomes after crossing over

D. 50 % gametes will be non viable due to deletion or duplication of chromatids

E. The gametes having recombinant chromatid or parental inversion chromatids will be non-viable

#Question id: 4487

#Unit 3. Fundamental Processes

Choose correct statements about nucleosome modifiers

#Question id: 4488

#Unit 3. Fundamental Processes

One component of thecomplex bears bromodomains and thus binds to acetylated nucleosomes better than to unacetylated nucleosomes. Thus, a gene bearing acetylated nucleosomes at its promoter will likely have a higher affinity for the transcriptional machinery than one with unacetylated nucleosomes.

#Question id: 4489

#Unit 3. Fundamental Processes

HSP70 gene from Drosophila. This gene, activated by heat shock, is controlled by two activators GAGA binding factor and HSF,In response to heat shock, HSF binds to specific sites at the promoter and recruits a kinase, P-TEFb (positive transcription elongation factor). What is the proper mechanism of pausing and release of Pol II ?

#Question id: 4490

#Unit 3. Fundamental Processes

The human immunodeficiency virus (HIV), which causes AIDS, transcribes its genes from a promoter controlled by P-TEFb (and SEC). Again, polymerase initiates transcription at that promoter, under the control of which activator?

#Question id: 4491

#Unit 3. Fundamental Processes

HIV transcribes its genes from a promoter controlled by P-TEFb, P-TEFb is brought to the stalled polymerase by an RNA-binding protein, not a DNA-bound one. The protein responsible is called

#Question id: 4492

#Unit 3. Fundamental Processes

If an enhancer activates a specific gene 400 kb away, what stops it from activating other genes whose promoters are within that range?