TLS Online TPP Program

#Question id: 5761


E. coli cells were spread on an agar plate, producing 1000 colonies.  The colonies are replica plated on two agar plates containing the antibiotic kanamycin and one agar plate without antibiotics.  All of the colonies are able to grow on the agar plate without antibiotic but only 4 colonies are able to grow on each of the agar plates containing kanamycin.  You notice that the four colonies that grew on each of the kanamycin containing plates are in the exact same position.  This demonstrates

#Unit 8. Inheritance Biology
  1. how to screen for environmental mutagens

  2. that mutations occur in prokaryotes as well as in eukaryotes

  3. that in some cases mutations are caused by the selective agent itself

  4. a direct correlation between the amount of the selective agent used and the number of resistant mutants (one-hit relationship)

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TLS Online TPP Program

#Question id: 5802

#Unit 8. Inheritance Biology

A wild type allele:

TLS Online TPP Program

#Question id: 5803

#Unit 8. Inheritance Biology

The mutation which causes sickle cell anemia in humans:

TLS Online TPP Program

#Question id: 5804

#Unit 8. Inheritance Biology

The gene that is mutated in cases of cystic fibrosis encodes an ion transporter protein normally expressed in the respiratory and digestive tracts along with other locations. Individuals homozygous for the most common mutation in this gene (ΔF508) died at very early ages prior to the advent of advanced medical intervention. Despite this, the mutation exists at relatively high frequency in populations of European descent. One potential explanation is that heterozygotes for such mutations may be relatively immune to the lethal effects of diseases such as typhoid fever. Which statement below is most accurate?

TLS Online TPP Program

#Question id: 5805

#Unit 8. Inheritance Biology

In Himalayan rabbits, the ears, feet, and muzzle are pigmented while the rest of the body is white. This is because they express an enzyme variant that is ineffective at body temperature but functions at the lower temperatures experienced by cells of the extremities. This is an example of:

TLS Online TPP Program

#Question id: 5806

#Unit 8. Inheritance Biology

Which of these is NOT a mechanism by which a chromosome rearrangement could affect gene function?

TLS Online TPP Program

#Question id: 5807

#Unit 8. Inheritance Biology

Which of the following would be an example of a germline mutation?