Changing the codon AGC to AGA represents a ____ mutation.

TLS Online TPP Program

#Question id: 24238

#Unit 4. Cell Communication and Cell Signaling

Which of the following does not exist as the major class of ECM molecules?

TLS Online TPP Program

#Question id: 24239

#Unit 4. Cell Communication and Cell Signaling

Integrins binds to their ligand which consist of

TLS Online TPP Program

#Question id: 24245

#Unit 4. Cell Communication and Cell Signaling

Following statements are regarding to Integrins receptors;

a. Integrins are the principal receptors used by animal cells to bind to the extracellular matrix. 

b. Integrins function as transmembrane linkers (integrators) between the extracellular matrix and the actin cytoskeleton. 

c. An integrin molecule is composed of four covalently associated transmembrane glycoprotein subunits called α2 and β2.

d. Integrins bind extracellular matrix (ECM) glycoproteins, Laminins, Collagens, Fibronectin and Vitronectin.

Which of the following statements are incorrect?

TLS Online TPP Program

#Question id: 24246

#Unit 4. Cell Communication and Cell Signaling

Fibronectin binds to integrin through: 

TLS Online TPP Program

#Question id: 24247

#Unit 4. Cell Communication and Cell Signaling

The binding of integrins to their ligands depends on

TLS Online TPP Program

#Question id: 24248

#Unit 4. Cell Communication and Cell Signaling

Which of the following subunit of each integrin act as primary determinant of its extracellular ligand specificity?