TLS Online TPP Program

#Question id: 30103


Direct sources of purine ring atoms in the de novo synthesis of IMP include:
1. glutamine.
2. a component of the tetrahydrofolate one-carbon pool.
3. aspartate.
4. glycine.

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. 1, 2 and 3
  2. 2 and 4
  3. 4 only
  4.  All four
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TLS Online TPP Program

#Question id: 28695

#Unit 2. Cellular Organization

O-linked oligosaccharides is representing the attachment of glycoproteins to the hydroxyl (–OH) group in which amino acid residue?

TLS Online TPP Program

#Question id: 28696

#Unit 2. Cellular Organization

N-linked oligosaccharide is attaching carbohydrate chain to the amide nitrogen of which amino acid residue?

TLS Online TPP Program

#Question id: 28697

#Unit 2. Cellular Organization

Biosynthesis of all N-linked oligosaccharides begins in the rough ER with a preformed branched oligosaccharide precursor containing_____
i) Glucose (Glc)
ii) Galactose
iii) Mannose (Man)
iv) N-acetylglucosamine (GlcNAc)
v) N-acetylgalactosamine (GalNAc)

TLS Online TPP Program

#Question id: 28698

#Unit 2. Cellular Organization

the oligosaccharide precursor is assembled on a membrane- attached anchor called dolichol phosphate, which is___

TLS Online TPP Program

#Question id: 28699

#Unit 2. Cellular Organization

First sugar residue is attached to dolichol by ___

TLS Online TPP Program

#Question id: 28700

#Unit 2. Cellular Organization

Biosynthesis of all N-linked oligosaccharides begins in the rough ER with a preformed branched oligosaccharide precursor Glc3Man9(GlcNAc)2, Which of the following statements is incorrect about these biosynthesis?
a) the oligosaccharide precursor is assembled on a membrane- attached anchor called dolichol phosphate
b) First sugar residue is attached to dolichol by a glycosidic bonds & the other
sugars are added by high-energy pyrophosphate
c) Two N- acetylglucosamine (GlcNAc) and five mannose residues are added one at a time to a dolichol phosphate on the lumen
d) Four mannose and three glucose  residue are added one to a dolichol phosphate on the luminal side