TLS Online TPP Program

#Question id: 30105


Methotrexate is an inhibitor of dihydrofolate reductase. Administration of methotrexate would inhibit:
1. de novo synthesis of UMP.
2. conversion of dUMP to dTMP.
3. conversion of IMP to GMP.
4. de novo synthesis of IMP

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. 1, 2 and 3
  2. 1 and 3
  3. 2 and 4
  4. All four
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TLS Online TPP Program

#Question id: 5362

#Unit 8. Inheritance Biology

From the following select the possible mode of inheritance and the probability that the daughter in generation III will show the trait.

TLS Online TPP Program

#Question id: 5363

#Unit 8. Inheritance Biology

A Southern blot using a probe that binds to the region spanning the mutation causing albinism detects one DNA fragment in homozygous normal individuals (A/A) and two fragments in albino individuals (a/a). Following banding pattern of three offspring of parents? Which of the following correct regarding parents?

TLS Online TPP Program

#Question id: 5364

#Unit 8. Inheritance Biology

The inheritance of a given disorder is recorded in families shown below: Based on the above limited information, which one of the following inheritance patterns of disorder was not shown in the family?

TLS Online TPP Program

#Question id: 5365

#Unit 8. Inheritance Biology

The following pedigree shows the inheritance of a common phenotype controlled by an autosomal recessive allele. The probability of carriers in the population is 1/3. What is the probability that a child from parents III-3 and III-4 will show the phenotype?

TLS Online TPP Program

#Question id: 5366

#Unit 8. Inheritance Biology

From the following select the possible mode of inheritance and the probability that the child in generation III will show the trait.

TLS Online TPP Program

#Question id: 5367

#Unit 8. Inheritance Biology

Following pedigree showing X link recessive disorder. Which of the following confirm a carrier female in a family?