TLS Online TPP Program

#Question id: 30114


In the case of monoclonal antibody production by hybridoma technology, myeloma cells used lack the enzyme hypxanthine - guanine phosphoriboxyl transferase(HGPRT) such that fused cells can only survive when selected on hypoxanthine-aminopterinthymdine (HAT). What is the role of aminopterin in this medium?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. To be used as cell cycle inhibitor of myeloma cells.
  2. To block the pathway for nucleotide synthesis.
  3. To facilitate fusion of Myeloid B cells and antibody producing B cells.
  4. To facilitate production of antibody producing B cells.
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TLS Online TPP Program

#Question id: 8897

#Unit 9. Diversity of Life Forms

Which of the following statements would be least acceptable to most zoologists?

TLS Online TPP Program

#Question id: 8898

#Unit 9. Diversity of Life Forms

Which extant chordates are postulated to be most like the earliest chordates in appearance?

TLS Online TPP Program

#Question id: 8899

#Unit 9. Diversity of Life Forms

A new species of aquatic chordate is discovered that closely resembles an ancient form. It has the following characteristics: external armor of bony plates, no paired lateral fins, and a suspension-feeding mode of nutrition. In addition to these, it will probably have which of the following characteristics?

TLS Online TPP Program

#Question id: 8900

#Unit 9. Diversity of Life Forms

Which of the following statements about craniates is (are) correct?
1. Craniates are more highly cephalized than are non-craniates.
2. Craniatesʹ genomic evolution includes duplication of clusters of genes that code for transcription factors.
3. The craniate clade is synonymous with the vertebrate clade.
4. Pharyngeal slits that can assist in gas exchange originated in craniates,
5. The two-chambered heart originated with the early craniates.

TLS Online TPP Program

#Question id: 8901

#Unit 9. Diversity of Life Forms

The origin of the craniates occurred at roughly the same time as the

TLS Online TPP Program

#Question id: 8902

#Unit 9. Diversity of Life Forms

What do craniates have that earlier chordates did not have?