In the case of monoclonal antibody production by hybridoma technology, myeloma cells used lack the enzyme hypxanthine - guanine phosphoriboxyl transferase(HGPRT) such that fused cells can only survive when selected on hypoxanthine-aminopterinthymdine (HAT). What is the role of aminopterin in this medium?

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#Question id: 32246

#Unit 2. Cellular Organization

Which one of the following act as GEF for GTPase switch protein at the ER membrane?

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#Question id: 12878

#General Aptitude

The radii of two solid iron spheres are 1 cm and 6 cm respectively.A hollow sphere is made by melting the two spheres. If the external radius of the hollow sphere is 9 cm, then its thickness (in cm) is

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#Question id: 13162

#Unit 4. Cell Communication and Cell Signaling

In the amoeba Dictyostelium discoideum, cAMP acts as an extracellular signalling molecule and binds to and signals via a G protein–coupled receptor; it is not a second messenger. Amoeba cells were transfected with genes encoding two fusion proteins: a Gα fused to cyan fluorescent protein (CFP), and a Gβ fused to yellow fluorescent protein (YFP). CFP normally fluoresces 490-nm light; YFP, 527-nm light. In which conditions fluorescence

energy transfer occur from CFP to YFP?

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#Question id: 11705

#Unit 7. System Physiology – Animal

Osmoregulatory adjustment via the atrial natriuretic peptide system can be triggered by:

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#Question id: 4120

#Unit 3. Fundamental Processes

Which of the following homolog matching is incorrectly matched with thier respective subunits?

	Bacterial	Archaea	RNAPI	RPAII	RPAIII
1.	B’	A’/A’’	RPA1	RPB1	RPC1
2.	B	K	RPA3	RPB2	RPC4
3.	aI	D	RPC5	RPB3	RPC5
4.	aII	L	RPC9	RPB11	RPC9