TLS Online TPP Program

#Question id: 31193


Mutations in β-catenin phosphorylation sites for the destruction complex kinases GSK3 or CK1 leads to following events, except?

#Unit 4. Cell Communication and Cell Signaling
  1. Reduce the formation of the destruction complex 
  2. Reduce the phosphorylations on β-catenin 
  3. Reduce degradation of β-catenin and allow free β-catenin to activate gene expression even in the absence of the normal Wnt signal
  4. Reduce degradation of β-catenin but not allowed β-catenin to activate gene expression even in the absence of the normal Wnt signal