Practice Questions

TLS Online TPP Program

#Question id: 31378

The following experimental manipulations were carried out with Xenopus embryo.
Manipulation X: Exposure to UV radiation leading to the failure of cortical rotation.
Manipulation Y: Gastrulae treated with lithium chloride.

The following statements were made with respect to the above manipulations. Which one of the following represents correct statement?

#Unit 5. Developmental Biology

The phenotype obtained due to manipulation X can be rescued by injection of BMP in 1-cell embryo.
Noggin mRNA will be enriched in embryos of manipulation X as compared to those of manipulation Y.
Injection of cDNA for chordin into dorsal blastomeres leads to the induction of a secondary axis.
If endogenous GSK3 is knocked out by a dominant-negative form of GSK3 in the ventral cells of the early embryo, a second axis forms.