TLS Online TPP Program

#Question id: 807


Which of the following forces can stabilize a normal DNA double-helix?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. Base-stacking is a non-covalent interaction that occurs between the relatively hydrophobic bases in the interior of the helix.

  2. Base-pairing is a non-covalent interaction that occurs between adjacent bases in the same strand of the DNA molecule.

  3. The hydrophilic sugar-phosphate groups are on the exterior of the helix where they can interact with each other.

  4. The deoxyribose rings form N-glycosidic bonds with the phosphate groups that link neighboring nucleotides.

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TLS Online TPP Program

#Question id: 4512

#Unit 3. Fundamental Processes

Some pre-mRNAs can be spliced in more than one way. Thus, mRNAs containing different selections of exons can be generated from a given pre-mRNA, called

TLS Online TPP Program

#Question id: 4513

#Unit 3. Fundamental Processes

Different snRNPs recognize the same (or overlapping) sequences in the pre-mRNA at different stages of the splicing reaction, which two snRNPs recognizing the 5’ splice site

TLS Online TPP Program

#Question id: 4514

#Unit 3. Fundamental Processes

What is true about coactivators,

A. The coactivators act directly by binding to the DNA

B. The coactivators act indirectly—not by binding to the DNA

C. Are required for essential communication between the activators and the complex composed of Pol II.

D. Are required for essential communication between the and the basal (or general) transcription factors.

TLS Online TPP Program

#Question id: 4515

#Unit 3. Fundamental Processes

Transcription Activators are,

A. Known to facilitate transcription at hundreds of promoters,

B. Specific for a few promoters,

C. Sensitive to the binding of signal molecules,

D. Providing the capacity to activate or deactivate transcription in response to a changing cellular environment.

TLS Online TPP Program

#Question id: 4516

#Unit 3. Fundamental Processes

High mobility group (HMG) proteins

A. are a common type of architectural regulator

B. facilitating the looping of the DNA

C. the binding is relatively very specific

D. are abundant in chromatin and bind to DNA with limited specificity.

TLS Online TPP Program

#Question id: 4517

#Unit 3. Fundamental Processes

Statement: When phosphorylated, CREB binds to CREs near certain genes and acts as a transcription factor, turning on the expression of these genes.

Explanation: I-Regulation can result from phosphorylation of Nuclear transcription factor

II- Activation of a protein kinase in the nucleus that phosphorylates specific DNA-binding proteins and thereby alters their ability to act as transcription factors.