In cells expressing mutant versions of Sar1 or ARF that cannot hydrolyze GTP, what would be the result?

a. Vesicle coats do not form and vesicle buds pinch off.

b. The mutant proteins cannot trigger disassembly of the coat all available coat subunits eventually become permanently.

c. Unable to fuse with target membranes.

d. Blocking of coat disassembly.

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#Question id: 12508

#Unit 8. Inheritance Biology

In this pedigree I 1 and II 2 have Becker muscular dystrophy which shows X-linked recessive inheritance. III 2 has oculocutaneous albinism which shows autosomal recessive inheritance with an incidence in the general population of 1 in 10 000. The disease status for both Becker muscular dystrophy and oculocutaneous albinism is unknown for IV 1 and IV 2.

What is the probability that III 3 is a carrier of oculocutaneous albinism?

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#Question id: 12509

#Unit 8. Inheritance Biology

In this pedigree I 1 and II 2 have Becker muscular dystrophy which shows X-linked recessive inheritance. III 2 has oculocutaneous albinism which shows autosomal recessive inheritance with an incidence in the general population of 1 in 10 000. The disease status for both Becker muscular dystrophy and oculocutaneous albinism is unknown for IV 1 and IV 2.

What is the probability that IV 1 is a carrier of oculocutaneous albinism? 

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#Question id: 12510

#Unit 8. Inheritance Biology

In this pedigree I 1 and II 2 have Becker muscular dystrophy which shows X-linked recessive inheritance. III 2 has oculocutaneous albinism which shows autosomal recessive inheritance with an incidence in the general population of 1 in 10 000. The disease status for both Becker muscular dystrophy and oculocutaneous albinism is unknown for IV 1 and IV 2.

What is the probability that IV 2 will be affected with Becker muscular dystrophy?

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#Question id: 12511

#Unit 8. Inheritance Biology

In this pedigree I 1 and II 2 have Becker muscular dystrophy which shows X-linked recessive inheritance. III 2 has oculocutaneous albinism which shows autosomal recessive inheritance with an incidence in the general population of 1 in 10 000. The disease status for both Becker muscular dystrophy and oculocutaneous albinism is unknown for IV 1 and IV 2.

What is the probability that IV 2 will be affected with oculocutaneous albinism?

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#Question id: 15003

#Unit 8. Inheritance Biology

Laurie met her husband Jim at a support group for families dealing with PKU (phenylketonurea), a recessive genetic disorder. Laurie and Jim both have one sister who is affected with PKU and no other family history of the disorder. They come to you as a genetic counselor to ask what their risk is of having an affected child. What do you tell them?

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#Question id: 15004

#Unit 8. Inheritance Biology

Which of the following statements about a pedigree would be most definitive in determining a recessive pattern of inheritance?