TLS Online TPP Program

#Question id: 7107


What would be the effect on the timing of somite formation, if a piece of the pre-somitic mesoderm of a chick embryo is rotated by 180° and reinserted in its original position?

#Unit 5. Developmental Biology
  1. there would be no effect because the embryo would regulate and development would proceed normally
  2. antero-posterior development would be blocked at that point, and more posterior structures would fail to form
  3. the rotated mesoderm will reverse the gradient of somite formation, so that somite formation posterior to the rotated mesoderm will begin in the posterior and move forward to meet the previously formed somites
  4. the timing of somite formation will be reversed in the rotated block only, proceeding from posterior to anterior, but the rest of the somites will form in a normal fashion, proceeding from anterior to posterior
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TLS Online TPP Program

#Question id: 1241

#Unit 4. Cell Communication and Cell Signaling

Which of the following is a common step in the opening/closing of ion channels by acetylcholine and rhodopsin binding to their receptors?

TLS Online TPP Program

#Question id: 1242

#Unit 4. Cell Communication and Cell Signaling

Rhodopsin, a light-sensitive GPCR whose role in vision is dependent on its phosphorylation status, is influenced in part by the protein arrestin.  Which of the following is TRUE with regard to rhodopsin and vision?

TLS Online TPP Program

#Question id: 1243

#Unit 4. Cell Communication and Cell Signaling

One form of receptor desensitization can be mediated by negative feedback involving phosphorylation of the receptor itself by a kinase activated downstream of a second messenger. The phosphorylated receptor likely:

TLS Online TPP Program

#Question id: 1244

#Unit 4. Cell Communication and Cell Signaling

Which type of experimental evidence shows that the intrinsic GTPase activity of the Gα subunit is important for terminating effector activation?

TLS Online TPP Program

#Question id: 1245

#Unit 4. Cell Communication and Cell Signaling

Many PTB-containing proteins act as docking sites for multiple proteins. If these proteins are involved in the RTK signal transduction pathway, they most likely:

TLS Online TPP Program

#Question id: 1246

#Unit 4. Cell Communication and Cell Signaling

An SH2-containing protein contains a mutation that changes its binding pocket such that tyrosine and phosphotyrosine bind with equal affinity. As a result, MEK activity: