TLS Online TPP Program

#Question id: 32718


When enzyme solutions are heated, there is a progressive loss of catalytic activity over time due to denaturation of the enzyme. A solution of the enzyme hexokinase incubated at 45oC lost 50% of its activity in 12 min, but when incubated at 45oC in the presence of a very large concentration of one of its substrates, it lost only 3% of its activity in 12 min. What is correct explanation

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. ES complex is more stable than the free enzyme
  2. Free enzyme is more stable than EP
  3. ES is more stable than EP
  4. Formation of EP stabilised enzymes