TLS Online TPP Program

#Question id: 7113


In flies, frogs, and chicks, gradients of morphogens determine the future antero-posterior and dorso-ventral axes of the developing embryo. How is the antero-posterior axis determined in C. elegans?

#Unit 5. Developmental Biology
  1. bicoid protein is translated in the anterior of the fertilized egg, leading to a gradient that determines the antero-posterior axis
  2. nodal triggers formation of an organizer that will determine the dorsal, and hence the anterior, side of the embryo
  3. beta-catenin becomes localized to the nucleus in the future anterior cells after fertilization
  4. sperm entry leads to a reorganization of the cytoskeleton and redistribution of maternally packaged PAR proteins, which in turn determine the antero-posterior axis