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TLS Online TPP Program

#Question id: 7123

In chicks, the formation of the neural tube relies on what cell biological processes?

#Unit 5. Developmental Biology
  1. Changes in cell shape in the neural plate are the only process required for neural tube formation.
  2. Changes in adhesiveness between the prospective neural tube cells and the prospective epidermis in the ectoderm are the only changes required for neural tube formation.
  3. Both changes in cell shape in the neural plate and changes in adhesion molecule expression in the neural tube are required during formation of the neural tube.
  4. Prospective neural tube cells in the ectoderm undergo medio-lateral intercalation, then involute and form the neural tube.
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TLS Online TPP Program

#Question id: 33913

#Unit 2. Cellular Organization

A. Underwinding of a B-DNA helix might facilitate or stabilize the formation of Z-DNA.
B. Underwinding aids in the transition by providing a local region of unwound DNA that allows the shift to Z-DNA.
C. Overwinding of a B-DNA helix might facilitate or stabilize the formation of Z-DNA.
D. Overwinding aids in the transition by providing a local region of unwound DNA that allows the shift to Z-DNA.

What is correct combination of statements
TLS Online TPP Program

#Question id: 33981

#Unit 2. Cellular Organization

The scaffold-associated regions are separated by loops of DNA. The scaffold itself may contain several proteins such as
A. Topoisomerase
B. SMCs
C. RNA Polymerase
TLS Online TPP Program

#Question id: 33982

#Unit 2. Cellular Organization

A. Chromosomes occupy chromosome territories in the nucleus and very much entangled with each other. 
B. Heterochromatic regions, silenced genes, and gene-sparse regions of chromosomes are typically localized to the nuclear periphery and center of nucleus. 
C. Active genes are often found at the borders and of chromosome territories
D. Active genes from several chromosomes may cluster in inter-chromosomal territories that are enriched in transcription machinery

Choose true and false
TLS Online TPP Program

#Question id: 33983

#Unit 2. Cellular Organization

Which of the protein hold heterochromatin region attached to nuclear wall
TLS Online TPP Program

#Question id: 33984

#Unit 2. Cellular Organization

Choose correct combination of statements 

A. Each chromosome contains many fragments of very long duplex of DNA, folded into a fiber that runs continuously throughout the chromosome.
B. During interphase, euchromatin, which is slightly densely packed than mitotic chromosomes. 
C. Regions of heterochromatin remain densely packed throughout interphase.
D. Various heterochromatic regions, especially those associated with centromeres, aggregate into a densely staining chromocenter
TLS Online TPP Program

#Question id: 33985

#Unit 2. Cellular Organization

To analyze existing MARs that are bound to the matrix in vivo, what is correct order of method 
A. Chromosomal loops decondensed by extracting the chromatin proteins. 
B. Removal of the DNA loops by treatment with restriction nucleases
C. Amplification of MAR and sequencing