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#Question id: 7127

The immunoglobulin genes are expressed in B-cells, and the b-globin gene is expressed in red blood cells. What manipulations might be carried out to get the b-globin gene to be expressed in B-cells?

#Unit 5. Developmental Biology
  1. The coding region of an immunoglobulin gene could be combined with the cis-regulatory region of the b-globin genes, and this artificial gene would then express b-globin in B-cells.
  2. The cis-regulatory region of the b-globin gene could be inserted into B-cells, which would then express their own version of the b-globin gene.
  3. The cis-regulatory region of an immunoglobulin gene could be combined with the coding region of the b-globin genes, and this artificial gene would then express b-globin in B-cells.

  4. The transcription factors GATA-1 and GATA-2 (which activate the b-globin gene in erythrocytes) could be introduced into B-cells, which would then express their own copy of the b-globin gene.

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#Question id: 12900

#General Aptitude

The perimeter of the base of a right circular cylinder is 'a' unit. If the volume of the cylinder is V cubic unit, then the height of the cylinder is 
TLS Online TPP Program

#Question id: 12901

#General Aptitude

The difference of perimeter and diameter of a circle is X unit. The diameter of the circle is 
TLS Online TPP Program

#Question id: 12902

#Unit 13. Methods in Biology

An extension of microarray technology may also be used to analyze tissue sections,this process is known as_____
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#Question id: 12903

#Unit 13. Methods in Biology

A gene isolation system that uses adapted vectors termed as_______
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#Question id: 12904

#Unit 13. Methods in Biology

Match the following:
1. Southern Blotting                               i. Melting temperature of DNA strand
2. DNA microchips                                   ii.oligonucleotide matching to DNA sample
3. ASO-PCR                                                 iii.DNA hybridization to oligo arrays
4. DGGE                                                        iv. labeled probe hybridization to DNA  
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#Question id: 12905

#Unit 13. Methods in Biology

Some gene/protein is used to identify the Disorder in humans
Match them correctly:
1. Tyrosine Kinase(TK)                        i. Atherosclerosis
2. HIV transactivator                          ii. Hypertension
3. Angiotensinogen                            iii. Kaposis Sarcoma
4. CET protein                                      iv. Cardiac Hypertrophy