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TLS Online TPP Program

#Question id: 33513

Which one of the following statements regarding mutations in the mitochondria during aging is INCORRECT?

#Unit 2. Cellular Organization
  1. Mutations in mitochondrial genome lead to defects in energy production.
  2. The mutation rate in mitochondria is much higher than that in the nucleus.
  3. Mutations reduce ROS production since electron transport is faulty.
  4. There is an enhanced rate of apoptosis in cells with mutant mitochondria. 
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TLS Online TPP Program

#Question id: 24235

#Unit 4. Cell Communication and Cell Signaling

In cultured cells, which of the following mutation in the EC5 domain of CDHR3 increases the cell-surface expression of CDHR3 and the binding and replication of RV-C?
TLS Online TPP Program

#Question id: 24236

#Unit 4. Cell Communication and Cell Signaling

Which of the following protein suppresses the expression of E-cadherin during epithelial-to-mesenchymal transition?
TLS Online TPP Program

#Question id: 24237

#Unit 4. Cell Communication and Cell Signaling

What are the two major components of the extracellular matrix?
TLS Online TPP Program

#Question id: 24238

#Unit 4. Cell Communication and Cell Signaling

Which of the following does not exist as the major class of ECM molecules?
TLS Online TPP Program

#Question id: 24239

#Unit 4. Cell Communication and Cell Signaling

Integrins binds to their ligand which consist of
TLS Online TPP Program

#Question id: 24245

#Unit 4. Cell Communication and Cell Signaling

Following statements are regarding to Integrins receptors;
a. Integrins are the principal receptors used by animal cells to bind to the extracellular matrix. 
b. Integrins function as transmembrane linkers (integrators) between the extracellular matrix and the actin cytoskeleton. 
c. An integrin molecule is composed of four covalently associated transmembrane glycoprotein subunits called α2 and β2.
d. Integrins bind extracellular matrix (ECM) glycoproteins, Laminins, Collagens, Fibronectin and Vitronectin.
Which of the following statements are incorrect?