Following statements are regarding thyroid hormone biosynthesis?

I. The basolateral membranes of thyrocytes facing the capillaries contain a antiporter that transports two Na⁺ ions and one I^– ion into the cell with each cycle, against the electrochemical gradient for I^–.

II. Na⁺/I^– symporter (NIS) is capable of producing intracellular I^– concentrations that are 20–40 times as great as the concentration in plasma.

III. TSH induces both NIS expression and the retention of NIS in the basolateral membrane, where it can mediate sustained iodide uptake.

#Question id: 28758

#Unit 2. Cellular Organization

In which organelles, the terminal signal sequences which are used for targeting protein or import of the proteins are not cleaved the target sequences after import?

#Question id: 28759

#Unit 2. Cellular Organization

C-terminal peroxisomal signal sequences used for importing into the peroxisomal matrix which involve___A_____ forms a multimeric complex with the _____B______receptor located on the peroxisomal membrane, according to figure A and B is?

#Question id: 28760

#Unit 2. Cellular Organization

Pex5 is a receptor which binds with peroxisomal-targeting sequence proteins in the cytosol that protein targeted into the peroxisomal matrix by forming a multimeric complex with the Pex14 receptor located on the peroxisomal membrane. After assembly, the matrix protein dissociates from Pex5 and Pex5 is then returned to the cytosol by which process?

#Question id: 28761

#Unit 2. Cellular Organization

#Question id: 28762

#Unit 2. Cellular Organization

For optimal activity, of lysosomal acid hydrolases they need to be___

a)Activation based on sensitivity to cleavage by endoglycosidase-D

b)Activation by proteolytic cleavage

c)Requires an acid environment

#Question id: 28763

#Unit 2. Cellular Organization

Lysosome an interior pH of about_____