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#Question id: 7191


In tunicate embryo, Presumptive endoderm originates from the vegetal A4.1 and B4.1 blastomeres. The specification of these cells coincides with the localization of β-catenin. Which of the following statement is incorrect?

#Unit 5. Developmental Biology
  1. Inhibition of β-catenin results in the loss of endoderm and its replacement by ectoderm in the tunicate embryo.
  2. increasing β-catenin synthesis causes an increase in the endoderm at the expense of the ectoderm (just as in sea urchins).
  3. The β-catenin transcription factor appears to function by activating the synthesis of the homeobox transcription factor Lhx3. Inhibition of the lhx3 message prohibits differentiation of endoderm.
  4. During the differentiation of endoderm β-catenin inhibits the synthesis of Lhx3. Expression of Lhx3 message causes differentiation of ectoderm.
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