TLS Online TPP Program

#Question id: 7204


Following statements are regarding to anterior-posterior polarity in planaria.

A. The anterior expression of Notum functions to antagonize the posteriorly produced Wnt, leading to head specification.

B. Regulation of the balance between Wnt and Notum signals may underlie not only head-tail specification but also regulation of organ size.

C. In addition, there appears to be an anterior-to-posterior gradient of Erk signaling that functions as a positive inducer of tail specification.

D. Wnt signaling achieves its repression of head regeneration by inhibiting Erk. Therefore, only in those more anterior regions lacking Wnt (due to Notum’s repression of Wnt) can Erk induce head regeneration.

Which of the following statements are incorrect?

#Unit 5. Developmental Biology
  1. A and B
  2. B only
  3. C only
  4. B and C