#Question id: 7220

The anterior-posterior polarity of the drosophila embryo is established while the oocyte is still in the egg chamber, and it involves interactions between the developing egg cell and the follicular cells that enclose it. Following are certain statements:

A. The gurken message appears to be synthesized in the oocyte, and it is transported into the nurse cells. Here it becomes localized between the nucleus of nurse cells and the cell membrane, and it is translated into Gurken protein.

B. Gurken signal is received by the follicle cells at that position through a receptor protein encoded by the torpedo gene.

C. This signal results in the “posterior -anteriorization” of these follicle cells.

D. Posterior follicle cells signals to recruit Par-1 protein organizes microtubules specifically with their minus (cap) and plus (growing) ends at the anterior and posterior ends of the oocyte, respectively.

E. The motor protein kinesin, is an ATPase that will use the energy of ATP to transport material to the plus end of the microtubule. Dynein, however, is a “minus-directed” motor protein that transports its cargo in opposite direction.

F. These zygotic messengers bicoid and nanos mRNAs are carried by motor proteins along the microtubules to the anterior and posterior ends of the oocyte, respectively.

Which combination of the above statements are correct?