Following statements are given regarding to the migration through primitive streak in chick.

A. Cells migrate to the primitive streak, and as they enter the embryo, the deep-moving cells give rise to the endodermal organs of the embryo, as well as to most of the extraembryonic membranes.

B. The migration of mesodermal cells through the anterior primitive streak and their condensation to form the chordamesoderm also appear to be controlled by FGF and Wnt signalling.

C. Wnt is expressed in the primitive streak and repels migrating cells away from the streak. 

D. Once cells migrate away from the streak, further movement of the mesodermal precursors appears to be regulated by FGF8 proteins.

Which of the following statement is incorrect?

#Question id: 2806

#Unit 2. Cellular Organization

Pseudogenes arise from the action of an enzyme

#Question id: 2807

#Unit 2. Cellular Organization

Huntington’s disease is an example of

a. an autosomal recessive disorder.    b. an autosomal dominant disorder.

c. a sex linked recessive disorder.      d. a sex linked dominant disorder.

#Question id: 2808

#Unit 2. Cellular Organization

A microsatellite is a type of polymorphism that

a. results from the change of a single nucleotide.

b. changes the recognition sequence for a restriction enzyme.

c. results from a variable number of repetitive sequences.

d. results from a chromosomal inversion.

#Question id: 2809

#Unit 2. Cellular Organization

In the human genome, one centimorgan or a 1 percent recombination frequency represents, on average, a distance of about

#Question id: 2810

#Unit 2. Cellular Organization

Which of the following steps is required to generate a knockout mouse?

a. microinjection of DNA into the pronucleus of a fertilized mouse egg

b. introduction of DNA into mouse embryonic stem cells

c. selection for cells containing the gene targeted insertion

d. expression of Cre protein during embryonic development

#Question id: 2811

#Unit 2. Cellular Organization

RNA interference is a method for inhibiting the function of specific genes using

a. single-stranded DNA.                     

b. double-stranded DNA.

c. single-stranded RNA.                     

d. double-stranded RNA.