Following statements were made regarding vulval development in C. elegans:

A. The formation of the anchor cell is mediated by lin-12, the C. elegans homologue of the Notch gene.

B. The formation of the anchor cell is mediated by lin-12, the C. elegans homologue of the Delta gene.

C. The lin-12 gene needs to function only in that cell destined to become the uterine precursor cell.

D. Presumptive Anchor cell also need lin-12.

E. Two cells originally synthesize both the signal for uterine differentiation (the LAG-2 protein, homologous to Delta) and the receptor for this molecule (the LIN-12 protein, homologous to Notch.

F. Only one cell synthesize both the signal for uterine differentiation (the LAG-2 protein, homologous to Delta) and the receptor for this molecule (the LIN-12 protein, homologous to Notch.

Which one of the following options represents a combination of incorrect statements?

#Question id: 1132

#Unit 4. Cell Communication and Cell Signaling

Which of the following become(s) active as a kinase when an activation lip residue is phosphorylated?

a. EpoR                       b. JAK             c. STAT           d. Ras              e. MAPK

#Question id: 1133

#Unit 4. Cell Communication and Cell Signaling

What tertiary structure characterizes all cytokines?

#Question id: 1134

#Unit 4. Cell Communication and Cell Signaling

Arrange the following proteins in the proper order in which they become activated in the MAPK signaling pathway:

a. MAP kinase                         b. MEK           c. Ras              d. Raf              e. RTK            

#Question id: 1135

#Unit 4. Cell Communication and Cell Signaling

Which of the following is a direct substrate of MAP kinase?

a. TCF             b. SRF             c. SRE             d. p90RSK      e. CREB

#Question id: 1136

#Unit 4. Cell Communication and Cell Signaling

Which of the following signaling pathways can be activated by activation of receptor tyrosine kinases?

a. phospholipase Cγ                b. PI-3 kinase

c. MAP kinase                         d. none of the above

#Question id: 1137

#Unit 4. Cell Communication and Cell Signaling

A loss-of-function mutation in PTEN phosphatase results in

a. increased cell proliferation.            

b. decreased cell proliferation.

c. increased apoptosis.                                   

d. decreased apoptosis.