TLS Online TPP Program

#Question id: 7245


Gradients of Wnt are essential for normal regeneration of a head and a tail by planaria. Which one of the following statement is incorrect?

#Unit 5. Developmental Biology
  1. In the absence of all Wnt signaling, caused by treatment of the excised body fragment with an inhibitory RNA specific for β-catenin, a two-headed planarian is regenerated.
  2. In the absence of Notum signaling, caused by treatment with an inhibitory RNA specific for Notum, a two-tailed planarian is regenerated; in this case, Wnt is present and active at both the anterior and posterior wounds, and thus two tails are formed.
  3. In the absence of both Wnt and Notum signaling, caused by treatment with inhibitory RNAs for both β-catenin and Notum, the phenotype is similar to that caused by the loss of Notum alone.
  4. In the absence of both Wnt and Notum signaling, caused by treatment with inhibitory RNAs for both β-catenin and Notum, the phenotype is similar to that caused by the loss of Wnt alone.