TLS Online TPP Program

#Question id: 7250


Following statements are regarding to signals that regulate axis extension in chick embryos.

A. In the stage 10 chick embryo, Fgf8 inhibits expression of the retinoic acid (RA) synthesizing enzyme Raldh2 in the presomitic mesoderm and the expression of the RA receptor RARβ in the neural ectoderm, thus preventing RA from triggering differentiation in the caudal-lateral epiblast cells and the caudal-most paraxial mesoderm.

B. Fgf8 inhibits Sonic hedgehog (Shh) expression in the neural tube floorplate, controlling the onset of ventral patterning genes.

C. FGF signaling is also required for expression of Delta1 in the medial portion of the caudal-lateral epiblast cells and promotes expression of Wnt8c.

D. Fgf8 decays in the caudal paraxial mesoderm, Wnt signaling, most likely provided by Wnt8c, now acts to promote Raldh2 in the adjacent paraxial mesoderm. RA produced by Raldh2 activity expresses Fgf8 and Wnt8c.

Which of the following statements are correct?

#Unit 5. Developmental Biology
  1. A and B
  2. B, C and D
  3. A, B and C
  4. C and D
More Questions
TLS Online TPP Program

#Question id: 7528

#General Aptitude

A 220 metres long train running at the speed of 110 kilometer per hour process another train running in opposite direction at the speed of 70 km per hour in 7 seconds. what is the length of the other train?

TLS Online TPP Program

#Question id: 7529

#General Aptitude

A jogger Running at 10 km/h allong side aur railway track in 150 m i head of the engine of a 300 M long train running at 64 km/hr in the same direction in how much time will the train pass the Jogger?

TLS Online TPP Program

#Question id: 7530

#General Aptitude

Two trains are moving in opposite directions at 72 km per hour and 90 km per hour . Their lengths are 500 m and 400 m respectively. the time taken by the Slower train to cross the faster train is

TLS Online TPP Program

#Question id: 7531

#General Aptitude

Two runners A and B start running from diametrically opposite points on a circular track in the same direction. If A runs at a constant speed of 8 km/h and B at a constant speed of 6 km/h and A catches up with B in 30 minutes , what is the length of the track?

TLS Online TPP Program

#Question id: 7532

#General Aptitude

A train running at 36 kmph crosses a mark on the platform in 8 seconds and takes 20 seconds to cross the platform. What is the length of the platform ?

TLS Online TPP Program

#Question id: 7533

#General Aptitude

A 3 m long car goes past a 4 m long truck at rest on the road .The speed of the car is 7 m/s . The time taken to go past is