TLS Online TPP Program

#Question id: 7265


Following statement regarding to the cascade of regulated RNA splicing controls drosophila sexual differentiation.

A. The Sex-lethal (Sxl) protein, encoded by the sex-lethal gene, is the first protein to act in the cascade and present only in female embryos.

B. Early in development, the Sxl gene is transcribed from a promoter that functions only in male embryos.

C. Later in development, this male-specific promoter is shut off, and another promoter for sex-lethal becomes active in both male and female embryos.

D. In male embryos, however, in the absence of early Sxl protein, exon 3 of the sex-lethal pre-mRNA is spliced to exon 2 to produce an mRNA that contains a stop codon early in the sequence.

Which of the following is correct?

#Unit 5. Developmental Biology
  1. A and B
  2. B and D
  3. A, C and D
  4. A only