#Question id: 3783
#Unit 3. Fundamental Processes
What is the basis for the difference in how the leading and lagging strands of DNA molecules are synthesized?
#Question id: 31255
#Unit 5. Developmental Biology
#Question id: 23041
#Unit 12. Applied Biology
#Question id: 26447
#Unit 3. Fundamental Processes
#Question id: 1258
#Unit 4. Cell Communication and Cell Signaling
Following statements are regarding to the desensitization mechanism of GPCR.
A. Several residues in the cytosolic domain of the β-adrenergic receptor are phosphorylated by the enzyme rhodopsin kinase.
B. β-Arrestin binds to specific phosphorylated tyrosine residues in the C-terminal segment of G protein–coupled receptors (GPCRs).
C. Clathrin and AP2, two other proteins bound by β-arrestin, promote endocytosis of the receptor.
D. β-Arrestin also functions in transducing signals from activated receptors by binding to and activating several cytosolic protein kinases like Src activates the MAP kinase pathway, leading to phosphorylation of key transcription factor.
Which of the following combination is incorrect?