#Question id: 2888
#Unit 2. Cellular Organization
Repressive complexes have been discovered that are composed of multiple repressing proteins bound to RNAs many kilobases in length that do not contain long open reading frames and are consequently called long noncoding RNAs or lncRNAs. Which of the following statements is correct regarding the regulation of these lncRNAs?
#Question id: 2889
#Unit 2. Cellular Organization
The edges of each base pair are exposed in the major and minor grooves, creating a pattern of hydrogen-bond donors and acceptors and of hydrophobic groups (allowing for Vander Waals interactions) that identifies the base pair. The edge of an C : G base pair displays the following chemical groups in the following order in the major groove:
#Question id: 2890
#Unit 2. Cellular Organization
Match individual variant histones i) to iv) to one or more of the possible functions listed in a) to g).
| Variant histones | Functions |
| i) CENP-A | a) DNA replication |
| ii) H2A.X | b) As a barrier to stop heterochromatin spreading |
| iii) H2A.Z | c) DNA repair |
| iv) H3.3 | d) Transcriptional activation |
| e) Kinetochore assembly | |
| f) Recombination | |
| g) Genome maintenance |
#Question id: 2891
#Unit 2. Cellular Organization
Which of the following statements regarding the Structural Maintenance Chromosomal proteins is correct?
A. The cohesins, along with a third protein, kleisin, are thought to form a ring around the replicated chromosomes.
B. Condensin binding causes the DNA to become underwound, in contrast to the overwinding induced by the binding of nucleosomes.
C. Cohesins are made up of pairs of Smc1 and Smc3 proteins, and condensins consist of Smc2-Smc4 pairs.
D. The primary structure of SMC proteins consists of three distinct domains.
#Question id: 2892
#Unit 2. Cellular Organization
The edges of each base pair are exposed in the major and minor grooves, creating a pattern of hydrogen-bond donors and acceptors and of hydrophobic groups (allowing for Vander Waals interactions) that identifies the base pair. The edge of an T : A base pair displays the following chemical groups in the following order in the major groove:
#Question id: 2893
#Unit 2. Cellular Organization
Which of the following statement regarding the Nucleosome-remodeling complexes is CORRECT?