TLS Online TPP Program

#Question id: 723


Common structural elements in proteins such as α-helices or β-sheets are characterized by uniformly repeating, energetically favorable main chain conformations which additionally exhibit a completely saturated hydrogen-bonding network of the main chain NH and CO groups. Although polyproline or polyglycine type II helices (PPII or PGII ) are frequently found in proteins, they are not considered as equivalent secondary structure elements. Which of the following statements are correct about PP and PGs.

A. PGII -like helices form hexagonal bundles which appear to fulfill the criterion of a (largely) saturated hydrogen-bonding network of the main-chain groups

B. main chain NH and CO groups of the central PGII -helix are saturated by either intra- or intermolecular hydrogen-bonds, resulting in a self-contained hydrogen-bonding network

C. The formation of the right-handed PPI helix is possible only with proline residues because of the required cis conformation. 

D. PPII helices seem to be stabilized by main chain-water hydrogen bonds (in the absence of main chain- main chain H-bonds), and tend to have a regular pattern of hydrogen bonds with water. After this, it is not surprising, that PPII helices are found mostly on the protein surface.

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. A & B only  

  2. A, B & C Only      

  3. B, C & D Only

  4. A, B, C & D

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TLS Online TPP Program

#Question id: 4705

#Unit 11. Evolution and Behavior

Darwin and Wallace's theory of evolution by natural selection was revolutionary because it ________.

TLS Online TPP Program

#Question id: 4706

#Unit 11. Evolution and Behavior

Which of the following statements best explains why modification or change in an organ or tissue during the lifetime of an individual is not inherited?

TLS Online TPP Program

#Question id: 4707

#Unit 11. Evolution and Behavior

For which one of the following observations were both Lamarck's hypothesis and Darwin's hypothesis in complete agreement?

TLS Online TPP Program

#Question id: 4708

#Unit 11. Evolution and Behavior

The following questions refer to the figure below, which shows an outcrop of sedimentary rock whose strata are labeled A-D. If x indicates the fossils of two closely related species, neither of which is extinct, then their remains may be found in how many of these strata?

TLS Online TPP Program

#Question id: 4709

#Unit 11. Evolution and Behavior

 The horizontal axis of the cladogram depicted below is a timeline that extends from 100,000 years ago to the present; the vertical axis represents nothing in particular. The labeled branch points on the tree (V-Z) represent various common ancestors. Let's say that only since 50,000 years ago has there been enough variation between the lineages depicted here to separate them into distinct species, and only the tips of the lineages on this tree represent distinct species.

 In Darwin's tree of life, each fork in the tree represents ________.

TLS Online TPP Program

#Question id: 4710

#Unit 11. Evolution and Behavior

The horizontal axis of the cladogram depicted below is a timeline that extends from 100,000 years ago to the present; the vertical axis represents nothing in particular. The labeled branch points on the tree (V-Z) represent various common ancestors. Let's say that only since 50,000 years ago has there been enough variation between the lineages depicted here to separate them into distinct species, and only the tips of the lineages on this tree represent distinct species.

 Which pair of scientists below would probably have agreed with the process that is depicted by this tree?