Phytochrome-mediated control of photomorphogenesis is linked to many other gene functions. The following statements are made on the mechanism of phytochrome action:

a) COP1, negative regulator of photomorphogenesis, is a component of the E3 ubiquitin ligase complex that targets photomorphogenesis-promoting proteins for degradation such as phyA

b) Light-dependent export of COP1 to the cytoplasm is a slow process, requires long exposure to light

c) The absence of COP1 in the cytosol permits the accumulation of transcriptional activators necessary for photomorphogenic development

d) The COP1–SPA1-E3 ligase complex is also responsible for the ubiquitination and proteasomal degradation of photomorphogenesis-promoting proteins, such as HY5

Which one of the following combinations is correct?

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#Question id: 12505

#Unit 8. Inheritance Biology

The marker genotype for I 2 must have been:

TLS Online TPP Program

#Question id: 12506

#Unit 8. Inheritance Biology

Using the linked markers III 3 can be told that:

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#Question id: 12507

#Unit 8. Inheritance Biology

In this pedigree I 1 and II 2 have Becker muscular dystrophy which shows X-linked recessive inheritance. III 2 has oculocutaneous albinism which shows autosomal recessive inheritance with an incidence in the general population of 1 in 10 000. The disease status for both Becker muscular dystrophy and oculocutaneous albinism is unknown for IV 1 and IV 2.

What is the probability that III 3 is a carrier of Becker muscular dystrophy?

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#Question id: 12508

#Unit 8. Inheritance Biology

In this pedigree I 1 and II 2 have Becker muscular dystrophy which shows X-linked recessive inheritance. III 2 has oculocutaneous albinism which shows autosomal recessive inheritance with an incidence in the general population of 1 in 10 000. The disease status for both Becker muscular dystrophy and oculocutaneous albinism is unknown for IV 1 and IV 2.

What is the probability that III 3 is a carrier of oculocutaneous albinism?

TLS Online TPP Program

#Question id: 12509

#Unit 8. Inheritance Biology

In this pedigree I 1 and II 2 have Becker muscular dystrophy which shows X-linked recessive inheritance. III 2 has oculocutaneous albinism which shows autosomal recessive inheritance with an incidence in the general population of 1 in 10 000. The disease status for both Becker muscular dystrophy and oculocutaneous albinism is unknown for IV 1 and IV 2.

What is the probability that IV 1 is a carrier of oculocutaneous albinism? 

TLS Online TPP Program

#Question id: 12510

#Unit 8. Inheritance Biology

In this pedigree I 1 and II 2 have Becker muscular dystrophy which shows X-linked recessive inheritance. III 2 has oculocutaneous albinism which shows autosomal recessive inheritance with an incidence in the general population of 1 in 10 000. The disease status for both Becker muscular dystrophy and oculocutaneous albinism is unknown for IV 1 and IV 2.

What is the probability that IV 2 will be affected with Becker muscular dystrophy?