TLS Online TPP Program

#Question id: 754


If the twisting of the DNA is in the same direction as that of the double helix, that is the helix is twisted up before closure, this form of super coiling is known as;

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. negatively supercoiled

  2. positively supercoiled

  3. L form supercoiled

  4. Z form supercoiled

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TLS Online TPP Program

#Question id: 23110

#Unit 2. Cellular Organization

Individual nucleosomes can be obtained by treating chromatin with the endonuclease micrococcal nuclease (MNase), which cuts the DNA between nucleosomes, a region known as 

TLS Online TPP Program

#Question id: 23111

#Unit 2. Cellular Organization

Choose the correct option 
a. Individual nucleosomes can be obtained by treating chromatin with the endonuclease micrococcal nuclease (MNase), which cuts the DNA between nucleosomes, a region known as H2A-H2B dimer region. 
b. Individual nucleosomes can be obtained by treating chromatin with the endonuclease micrococcal nuclease (MNase), which cuts the DNA between nucleosomes, a region known as linker DNA.
c. Mononucleosomes typically have 200 bp DNA. End-trimming reduces the length of DNA first to 165 bp and then generates core particles with 146 bp.
d. Mononucleosomes typically have 200 bp DNA. End-trimming reduces the length of DNA first to 165 bp and then generates core particles with 200 bp.

TLS Online TPP Program

#Question id: 23112

#Unit 2. Cellular Organization

Chromatin on treatment with Mnase generates fragments, as the time and concentration of Mnase increase various fragments are observed choose the incorrect statement 

TLS Online TPP Program

#Question id: 23113

#Unit 2. Cellular Organization

Chromatin on digestion with Mnase can be result on centrifugation and electrophoresis, on sedimentation the following result is obtained 

TLS Online TPP Program

#Question id: 23114

#Unit 2. Cellular Organization

What is the minimum length to stabilize nucleosome 

TLS Online TPP Program

#Question id: 23115

#Unit 2. Cellular Organization

The assay which is used in DNA foot-printing to identify the nitrogenous base sequences