With respect to microRNAs, which, if any, of the following statements, is FALSE?)

A. MicroRNA genes often occur in gene clusters within introns of protein-coding genes and are usually transcribed by RNA polymerase II.

B. Like an mRNA a miRNA is initially produced as a larger precursor RNA that, like the great majority of mRNAs, usually has a 5’ cap and a poly(A) tail.

C. MicroRNAs are produced by germ-line cells only.

D. A miRNA is initially produced as a duplex RNA but in order to work it needs to be converted into a single-strand RNA.

E. MicroRNAs usually work as transcription factors.

#Question id: 2774

#Unit 2. Cellular Organization

The DNA and protein sequences of the -tubulin genes in humans and in fish are similar, and because each arose due to speciation, these genes would be considered:

#Question id: 2775

#Unit 2. Cellular Organization

To examine the folding and compaction of chromatin during mitosis, you will need to isolate and stain chromosomes at a particular stage using a special spreading preparation technique. For the best analysis, the chromosomes must be at which one of the following stages?

#Question id: 2776

#Unit 2. Cellular Organization

There are five major types of histone proteins, but only four of them are considered as core histones. Which one of the following is NOT considered a core histone protein?

#Question id: 2777

#Unit 2. Cellular Organization

Histone modifications play integral roles in chromatin condensation and function. Which of the following is NOT considered to be a histone modification?

#Question id: 2778

#Unit 2. Cellular Organization

You are studying the regulation of a group of genes and have determined that the full activation of transcription of these genes occurs when histone acetyl transferases have made post-translational modifications specifically to which one of the following amino acids?

#Question id: 2780

#Unit 2. Cellular Organization

Which of the following pairs of proteins are considered to be paralogous?