TLS Online TPP Program

#Question id: 808


Which, if any, of the following statements is false?

#Unit 1. Structure and Function of Biomolecules
  1. RNA interference (RNAi) is a cellular defense mechanism that is triggered by the presence in cells of unnatural double-stranded RNA, as can occur after viral infections.

  2. RNAi therapy is a type of RNA-targeted therapy in which specific double-stranded RNA constructs are engineered to appear in diseased cells in order to incite the cells to destroy any RNA that contains the same sequence.

  3. By destroying RNAs that are related to a specifically introduced genetic construct, artificial RNAi is effectively a type of gene-specific silencing.

  4. RNAi therapy is best suited to silencing genes so as to replicate a phenotype caused by loss-of-function mutations.

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TLS Online TPP Program

#Question id: 4233

#Unit 3. Fundamental Processes

A particular triplet of bases in the coding sequence of DNA is AAA. The anticodon on the tRNA that binds the mRNA codon is __.

TLS Online TPP Program

#Question id: 4234

#Unit 3. Fundamental Processes

Accuracy in the translation of mRNA into the primary structure of a polypeptide depends on specificity in the __.

TLS Online TPP Program

#Question id: 4235

#Unit 3. Fundamental Processes

What would be the consequence of a mutation in a bacterial cell that produces a defective aminoacyl-tRNA synthetase that attaches a lysine instead of the normal phenylalanine to tRNAs with the anticodon AAA?

TLS Online TPP Program

#Question id: 4236

#Unit 3. Fundamental Processes

In bacteria, there are 61 mRNA codons that specify an amino acid, but only 45 tRNAs. Which of the following statements explains this fact?

TLS Online TPP Program

#Question id: 4237

#Unit 3. Fundamental Processes

A part of an mRNA molecule with the following sequence is being read by a ribosome: 5′-CCGACG- 3′ (mRNA). The following charged transfer RNA molecules (with their anticodons shown in the 3′ to 5′ direction) are available. Two of them can correctly match the mRNA so that a dipeptide can form. Which of the following dipeptides will form from this mRNA?

tRNA AnticodonAmino Acid
GGCProline
CGUAlanine
UGCThreonine
CCGGlycine
ACGCysteine
CGGAlanine

TLS Online TPP Program

#Question id: 4238

#Unit 3. Fundamental Processes

Use the following information to answer the question. A part of an mRNA molecule with the following sequence is being read by a ribosome: 5′-CCGACG- 3′ (mRNA). The following charged transfer RNA molecules (with their anticodons shown in the 3′ to 5′ direction) are available. Two of them can correctly match the mRNA so that a dipeptide can form.

tRNA AnticodonAmino Acid
GGCProline
CGUAlanine
UGCThreonine
CCGGlycine
ACGCysteine
CGGAlanine