TLS Online TPP Program

#Question id: 11142


A researcher uses the chemical inhibitor cyanide to reduce ATP production in a neuron. What would be one effect of preventing ATP production?

#Unit 7. System Physiology – Animal
  1. The sodium and potassium channels would all be closed.
  2. The membrane would become more permeable to sodium.
  3. Disruption to the normal "resting" distribution of potassium and sodium ions.
  4. A physical breakdown of the plasma membrane would occur.
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TLS Online TPP Program

#Question id: 5132

#Unit 5. Developmental Biology

Upon secretion of wnt, When Wnt attaches to the Frizzled receptor on a responding cell, the cell secretes Notum, a hydrolase that associates with glypican and then cleaves off Wnt’s attached lipids in a process of deacylation or delipidation. This process:

TLS Online TPP Program

#Question id: 5133

#Unit 5. Developmental Biology

Identify the correct ligands in both receptor serine kinase pathway.

 

TLS Online TPP Program

#Question id: 5134

#Unit 5. Developmental Biology

Match the following cleavage patterns with the species in which they occur.

SpeciesCleavage Pattern
A. Flatwormi. Meroblastic discoidal
B. Frogii. Meroblastic superficial
C. Birdsiii. Holoblastic displaced radial
D. Insectiv. Holoblastic spiral

TLS Online TPP Program

#Question id: 5135

#Unit 5. Developmental Biology

In xenopus, result of tissue transplantation during early and late gastrulae

(A) Cells of early newt gastrula exhibit conditional development.

(B) Cells of early newt gastrula exhibit autonomous development

(C) Cells of late newt gastrula exhibit conditional development.

(D) Cells of late gastrula exhibit autonomous development.

The correct inferences are:

TLS Online TPP Program

#Question id: 5136

#Unit 5. Developmental Biology

Some statements regarding to hippo pathway.

A. The Hippo signal transduction pathway have a dedicated ligand or receptor

B. Hippo stands for one of several important kinases that are critical for organ size control

C. It was first identified in Drosophila, where its loss resulted in a “hippopotamus”-shaped phenotype due to excessive growth

D. Gain of Hippo causes cells to divide significantly faster while slowing apoptosis

E. overexpression of its main transcriptional effector, Yorkie causes cells to divide significantly faster while slowing apoptosis

Which of the following combination are incorrect?

TLS Online TPP Program

#Question id: 5137

#Unit 5. Developmental Biology

Match the correct animal and their mechanism of germplasm specification.

Animal

Specification of germ cells

a. Drosophila

i. germplasm is characterized by polar granules and PIE-1 protein, and segregates into P4 during cleavage 

b. Xenopus                                                

ii. germplasm localized in vegetal region of egg

c. mammals

iii. germplasm specified by oskar at posterior end of egg

d. c. elegans

iv. Have no germplasm