#Question id: 1253
#Unit 4. Cell Communication and Cell Signaling
Following statements are regarding to the wnt signalling.
A. Wnt proteins interact with several cell-surface proteins and activate multiple downstream signal transduction pathways. The principal signaling receptor for Wnt proteins is Frizzled (Fz), which contains seven transmembrane α helices.
B. The palmitate attached to the Wnt protein binds to a specific site on the Fz intracellular domain and stabilizes the Wnt-Fz complex.
C. “canonical” Wnt signaling pathway uses a second transmembrane protein, LRP, that associates with Frizzled in a Wnt signal– dependent manner.
D. In the resting state, two kinases in the complex, casein kinase 1 (CK1) and GSK3, sequentially phosphorylate β-catenin on multiple tyrosine residues.
Which of the following statements are correct?
#Question id: 217
#Unit 1. Molecules and their Interaction Relevant to Biology
Which substance would make a good ligand for biotin on the matrix of an affinity chromatography column?
#Question id: 12116
#Unit 10. Ecological Principles
#Question id: 11904
#Unit 7. System Physiology – Animal
Which of the following changes would be expected in a patient with diabetes insipidus due to a lack of antidiuretic hormone (ADH) secretion?
#Question id: 21391
#Unit 12. Applied Biology