TLS Online TPP Program

#Question id: 836


To predict the structure of any protein the most simplest and reliable approach is,

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. structural genomics

  2. homology modeling

  3. Threading

  4. Rosetta program

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TLS Online TPP Program

#Question id: 2986

#Unit 2. Cellular Organization

During ubiquitin-mediated protein degradation in various events of cell cycle, ubiquitin-protein ligases ubiquitinylate substrate proteins, marking them for degradation by proteasomes. Cyclins are degraded through the action of two different ubiquitin-protein ligases, SCF and the anaphase-promoting complex or cyclosome. Following statements are regarding to SCF and APC/C.

A. SCF controls the G1–S phase transition by degrading G1/S phase cyclins and, CDK inhibitory proteins.

B. APC/C degrades S phase and mitotic cyclins, thereby promoting the exit from mitosis.

C. SCF and APC/C are multi-subunit ubiquitin-protein ligases that belong to the RING finger family of ubiquitin protein ligases.

D. SCF and APC/C belong to the different ubiquitin-protein ligase family, their regulation is same.

E. SCF recognizes its substrates only when they are phosphorylated.

F. SCF and APC/C both recognizes its substrates only when they are phosphorylated.

Which of the following is incorrect?

TLS Online TPP Program

#Question id: 32336

#Unit 2. Cellular Organization

Which of the following actin binding protein is found predominantly in cells in which actin filaments need to be highly stabilized?

TLS Online TPP Program

#Question id: 15417

#Unit 5. Developmental Biology

Sequence of amphibian lens induction postulated by experiments on embryos of the frog Xenopus laevis ; EXCEPT

TLS Online TPP Program

#Question id: 26550

#Unit 3. Fundamental Processes

Choose which of the following statement is correct  
a. Ribosomes PTC do  not remove EJC
b. Stalled EJC recruits Upf
c. Upf recruits 5’-3’ decapping & 3’-5’ deadynylation 
d. Finally mRNA is decayed in NMD process

TLS Online TPP Program

#Question id: 3447

#Unit 11. Evolution and Behavior

Which of the following does not have a coefficient of relatedness of 0.5?