TLS Online TPP Program

#Question id: 11513


Organisms whose life history adaptation is called semelparity

#Unit 10. Ecological Principles
  1. Produce young only late in life
  2. Produce a large batch of young and die
  3. Produce young over most of their life
  4. Produce a single offspring near the end of their reproductive potential
More Questions
TLS Online TPP Program

#Question id: 1512

#Unit 4. Cell Communication and Cell Signaling

There is evidence that the accumulation of abnormal or damaged proteins due to impairment of the pathway contributes to a number of neurodegenerative diseases, including Alzheimer’s. In contrast, deliberately blocking the pathway in cancer cells could lead to a disruption of protein regulation that in turn could cause the apoptosis of the malignant cells. Accordingly, proteasome inhibitors have been developed for evaluation as anti-tumour agents against selected cancers. Bortezomib is one such inhibitor that targets the 26S proteasome, and in combination with other chemotherapeutic agents has been shown to have therapeutic potential. In contrast to the long-term control, there are several mechanisms by which the activity of an enzyme can be altered almost instantaneously:

A. Reversible inhibition by small molecules (drugs)

B. Product inhibition

C. Allosteric regulation

D. Reversible covalent modification

Which of the above mechanism follow the process of negative-feedback control and ADP-ribosylation respectively?

TLS Online TPP Program

#Question id: 22012

#Unit 1. Molecules and their Interaction Relevant to Biology

Increasing the Km value, the Lineweaver-Burk equation shift

TLS Online TPP Program

#Question id: 13144

#Unit 8. Inheritance Biology

Shell coiling of the snail Limnaea peregra(genetic maternal effect)  the shell coils (s+s+) which is termed dextral coiling, while some snails exhibiting sinistral coiling (ss). The allele for dextral (s +) is dominant over the allele for sinistral (s). If a male homozygous for dextral alleles (s+s+) is crossed with a female homozygous for sinistral alleles (ss) all of the F1 are heterozygous (s+s) and have a sinistral shell. If these F1 snails are self-fertilized, what is the phenotype of the F2 snail?

TLS Online TPP Program

#Question id: 16125

#Unit 13. Methods in Biology

You are studying regulation of the yeast enzyme glutamine synthetase (GS), which is encoded by the GLN1 gene. You have isolated two mutants, designated gln2– and gln3–, that give decreased GS activity. Mating of either gln2– or gln3– haploids to wild type produces heterozygous diploids that show normal amounts of GS expression. When you cross either a gln2– or gln3– haploid to a gln1– strain the resulting diploids show normal expression of GS.              
From these experiments,  Classify  the  gln2– and gln3– mutations in terms of their basic genetic properties explaining the rationale behind your conclusions. Based on these properties make a proposal for the types of regulatory functions affected by the gln2– and gln3– mutations.

TLS Online TPP Program

#Question id: 26543

#Unit 3. Fundamental Processes

What are the function of P-TEFb  
a.It Phosphorylate NELF & DSIF
b.It Phosphorylate S2/7 OF CTD
c.It Phosphorylate SPT 5