TLS Online TPP Program

#Question id: 864


Which one is not the appropriate function of Heat Shock Proteins;

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. Minimize heat and stress damage to proteins

  2. Bind to nascent polypeptides to prevent premature folding

  3. Facilitate only disassembly of multi protein complexes

  4. Facilitate correct folding of proteins by minimizing aggregation and other misfolding

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TLS Online TPP Program

#Question id: 28697

#Unit 2. Cellular Organization

Biosynthesis of all N-linked oligosaccharides begins in the rough ER with a preformed branched oligosaccharide precursor containing_____
i) Glucose (Glc)
ii) Galactose
iii) Mannose (Man)
iv) N-acetylglucosamine (GlcNAc)
v) N-acetylgalactosamine (GalNAc)

TLS Online TPP Program

#Question id: 28698

#Unit 2. Cellular Organization

the oligosaccharide precursor is assembled on a membrane- attached anchor called dolichol phosphate, which is___

TLS Online TPP Program

#Question id: 28699

#Unit 2. Cellular Organization

First sugar residue is attached to dolichol by ___

TLS Online TPP Program

#Question id: 28700

#Unit 2. Cellular Organization

Biosynthesis of all N-linked oligosaccharides begins in the rough ER with a preformed branched oligosaccharide precursor Glc3Man9(GlcNAc)2, Which of the following statements is incorrect about these biosynthesis?
a) the oligosaccharide precursor is assembled on a membrane- attached anchor called dolichol phosphate
b) First sugar residue is attached to dolichol by a glycosidic bonds & the other
sugars are added by high-energy pyrophosphate
c) Two N- acetylglucosamine (GlcNAc) and five mannose residues are added one at a time to a dolichol phosphate on the lumen
d) Four mannose and three glucose  residue are added one to a dolichol phosphate on the luminal side

TLS Online TPP Program

#Question id: 28701

#Unit 2. Cellular Organization

Which of the following inhibitors inhibits the synthesis of all N-linked oligosaccharides in cells?

TLS Online TPP Program

#Question id: 28702

#Unit 2. Cellular Organization

Oligosaccharyl transferase enzyme involves to transferred precursor oligosaccharide