TLS Online TPP Program

#Question id: 867


Match the correct diseases with their precursors

Disease

Protein or precursor involved in disease

1. Cystic fibrosis

a. Prion protein

2. Creutzfeldt–Jakob disease

b. CFTR

3. Familial hypercholesterolaemia

c. LDL receptor

4. fatal familial insomnia

d. β-amyloid protein

5. Alzheimer’s disease

e. β-hexosaminidase

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. 1-b, 2-e, 3-e, 4-a, 5-d

  2. 1-b, 2-c, 3-c, 4-e, 5-d

  3. 1-b, 2-a, 3-c, 4-a, 5-d

  4. 1-d, 2-a, 3-d, 4-e, 5-b

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#Question id: 10256

#Unit 6. System Physiology – Plant

Both sucrose synthase and invertases can degrade sucrose for glycolysis, what will happen if one of the enzymes is absent or mutant?

TLS Online TPP Program

#Question id: 28644

#Unit 2. Cellular Organization

CDK activity is high in which phase of the cell cycle?

TLS Online TPP Program

#Question id: 129

#Unit 1. Molecules and their Interaction Relevant to Biology

Glycine is not a stereoisomer because

TLS Online TPP Program

#Question id: 7264

#Unit 5. Developmental Biology

The Dictyostelia social amoebas are found in a wide range of soil habitats. They can come together to form a fruiting structure, in which a proportion of cells are sacrificed to build the stalk and the remainder differentiate into resilient dormant spores. This multicellular life cycle is common to all Dictyostelids. It consists of an interconnected programme of cell movement and cell differentiation, and has been intensively studied in the model organism D. discoideum. Few mutants (Column A) and phenotypes (Column B) are listed in the table given below.

    Column A

    Column B

A. Loss of function of cAMP-dependent protein kinase (PKA)

i. cell develop normally but unable to germinate

B. Loss of function of RegA

ii. Loose aggregate form

C. Loss of function of adenylate cyclase B

iii. No aggregation

D. Loss of function of gp80

iv. accumulation of cAMP and PKA activation

 Match the correct mutant with the observed phenotype.

TLS Online TPP Program

#Question id: 24482

#Unit 3. Fundamental Processes

Which of the following statement is true regarding RNA polymerase III 
1. RNA polymerase III transcribes a set of short genes
2. The classical class III genes (types I and II) have promoters that lie wholly within the genes.
3. Box A and Box B is the characteristics of RNA polymerase III type II
4. Box A and Box B is the characteristics of RNA polymerase III type I