Prion protein is a normal constituent of brain tissue in all mammals which of the following statements are correct regarding prion protein

a) Strains of mice lacking the gene for PrP suffer no obvious ill effect

b) Illness occurs only when the normal cellular PRP or prpc occurs in an altered confirmation called PrPsc

c) The interaction of prpsc with the prpc converts the letter to prpsc initiating a Domino effect in which more and more the brain proteins converted to the disease causing form

d) the structure of prpsc is very different with much of the structure converted to amyloid like Alpha sheet.

TLS Online TPP Program

#Question id: 28063

#Unit 1. Structure and Function of Biomolecules

Characteristics of Thermostable proteins are  

a. loosely packed core as evidenced by a high surface-to-volume ratio.

b. High amounts of Arg

c. High amount of Ala in helices

d. Stable at high temperature due to High protein’s hydrophobic core and high incidence of salt bridges

TLS Online TPP Program

#Question id: 28064

#Unit 1. Structure and Function of Biomolecules

Which of the following Techniques can be used to for Measuring Stability of protein    

a. DSC (calorimetry) 

b. Urea gradient gels 

c. FRET

d. EPR

Which of the following is correct

TLS Online TPP Program

#Question id: 28065

#Unit 1. Structure and Function of Biomolecules

Guanidinium ion and urea are  

TLS Online TPP Program

#Question id: 28066

#Unit 1. Structure and Function of Biomolecules

Which of the following parameter is measured during analysis for the Stability of protein by DSC (calorimetry) 

TLS Online TPP Program

#Question id: 28067

#Unit 1. Structure and Function of Biomolecules

The graph shown below is for Fluorescence emission spectra any protein X, The which of the following assumption can be made

TLS Online TPP Program

#Question id: 28068

#Unit 1. Structure and Function of Biomolecules

Which of the following addition of group represent acetylation?