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TLS Online TPP Program

#Question id: 878

Can a peptide bind more strongly to an unfolded than the same protein in a folded state?

#Unit 1. Molecules and their Interaction Relevant to Biology

  1. It will depend on the balance of favourable interactions (enthalpy) versus loss in conformational entropy. For the folded protein, the loss in conformational entropy is less upon binding.

  2. If the increased interactions for the unfolded protein can less than compensate the increased loss in conformational entropy then the net Gibbs free energy will be favourable.

  3. The unfolding do not cause the the appearance of hydrophobic sites of the surface of protein, so if the interaction of the peptide with the protein is depending on the hydrophobic site.

  4. If the binding site changed due to unfolding the binding will be stronger.

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TLS Online TPP Program

#Question id: 12138

#Unit 10. Ecological Principles

The oak tree pathogen Phytophthora ramorum has migrated 650 km in ten years. West Nile virus spread from New York State to 46 others states in five years. The difference in the rate of spread is probably related to
TLS Online TPP Program

#Question id: 12223

#Unit 10. Ecological Principles

Evidence shows  that some grasses benefit from being  grazed. Which of the following  terms would  best describe this plant-herbivore interaction?
TLS Online TPP Program

#Question id: 12224

#Unit 10. Ecological Principles

Which of the following terms best describes the interaction between termites and the protozoans that feed in their gut?
TLS Online TPP Program

#Question id: 12225

#Unit 10. Ecological Principles

Which of the following interactions can correctly be labeled coevolution?
TLS Online TPP Program

#Question id: 12226

#Unit 10. Ecological Principles

Which  of  the  following  types  of  species interaction is  correctly paired with  its  effects  on  the  density  of  the  two interacting populations?
TLS Online TPP Program

#Question id: 12227

#Unit 10. Ecological Principles

During the course of the formation of a parasite/host relationship, a critical first step in this evolution would be