A 68-year-old woman with hematemesis has heartburn and stomach pain. Endoscopy shows inflammation involving the gastric body and antrum as well as a small gastric ulcer. Biopsies were positive for Helicobacter pylori. H. pylori damages the gastric mucosa primarily by increasing mucosal levels of which substance?

TLS Online TPP Program

#Question id: 30112

#Unit 1. Molecules and their Interaction Relevant to Biology

With respect to the de novo synthesis of nucleotides, which one of the following statements is INCORRECT?

TLS Online TPP Program

#Question id: 30113

#Unit 1. Molecules and their Interaction Relevant to Biology

Aspartate (Asp) is an amino acid with the structure NH2-CH(CH2-COOH)COOH. Given below are biosynthetic processes occurring in cells:

A. protein synthesis

B. de novo synthesis of inosine monophosphate and orotic acid

C. synthesis of adenosine monophosphate from inosine monophosphate

D. glutathione synthesis

Which one of the following options correctly represents all the biosynthetic process( es) wherein Asp is involved as a precursor?

TLS Online TPP Program

#Question id: 30114

#Unit 1. Molecules and their Interaction Relevant to Biology

In the case of monoclonal antibody production by hybridoma technology, myeloma cells used lack the enzyme hypxanthine - guanine phosphoriboxyl transferase(HGPRT) such that fused cells can only survive when selected on hypoxanthine-aminopterinthymdine (HAT). What is the role of aminopterin in this medium?

TLS Online TPP Program

#Question id: 30115

#Unit 1. Molecules and their Interaction Relevant to Biology

The antibacterial trimethoprim is an inhibitor of 

TLS Online TPP Program

#Question id: 30115

#Unit 1. Molecules and their Interaction Relevant to Biology

The antibacterial trimethoprim is an inhibitor of 

TLS Online TPP Program

#Question id: 30116

#Unit 1. Molecules and their Interaction Relevant to Biology

During purine synthesis the activity of amidotransferase enzyme is inhibited by the antitumor agent, mark the correct one.