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TLS Online TPP Program

#Question id: 12186

In 2001, the Nobel Prize in Physiology or Medicine was awarded to three cell cycle scientists. Paul Nurse was recognized for his studies with the fission yeast S. pombe, in particular for the discovery and characterization of the wee1+ gene. What did the characterization of the wee1+ gene tell us about cell cycle control?

#Unit 2. Cellular Organization
  1. The dual-specificity protein kinase Wee1 phosphorylates CDKs on the activatory tyrosine 15.
  2. Yeast cells with a defective wee1+ gene activate S phase CDKs prematurely and hence experience premature entry into DNA replication. 
  3. Fission yeast cells carrying a CDK1 mutation in which the tyrosine 15 residue is replaced by phenylalanine (which is structurally similar to tyrosine but cannot be phosphorylated) show the premature mitotic CDK activation and entry into mitosis.
  4. The dual-specificity protein phosphatase Wee1 dephosphorylates CDKs on the inhibitory tyrosine 15.

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TLS Online TPP Program

#Question id: 903

#Unit 1. Molecules and their Interaction Relevant to Biology

Proteins segments which fold first can promote the folding of other sections of the protein into the native conformation by a process known as
TLS Online TPP Program

#Question id: 8928

#Unit 9. Diversity of Life Forms

An adult animal that possesses bilateral symmetry is most certainly also
TLS Online TPP Program

#Question id: 12650

#Unit 6. System Physiology – Plant

13-Hydroperoxy linolenic acid is produce from Linolenic acid through the octadecanoid pathway by the specific enzyme____
TLS Online TPP Program

#Question id: 18866

#Unit 13. Methods in Biology

In fluorescence microscopy, which of the following controls the removal of all light except blue light?
TLS Online TPP Program

#Question id: 15970

#Unit 12. Applied Biology

Nutritional requirements of embryo culture is mostly dependent on the endosperm and maternal tissue for nutrient supply is ___