#Question id: 5208
#Unit 11. Evolution and Behavior
Fragments of DNA have been extracted from the remnants of extinct wooly mammoths, amplified, and sequenced. These can now be used to
#Question id: 28982
#Unit 7. System Physiology – Animal
Tyrosine is transported into catecholamine-secreting neurons via
#Question id: 1520
#Unit 1. Molecules and their Interaction Relevant to Biology
Following statements are regarding to enzymatic processing of benzo(a)pyrene to a more potent mutagen and carcinogen.
A. Liver enzymes, particularly P-450 enzymes, modify benzo(a)pyrene in a series of reactions, producing 7,8-diol-9,10-epoxide, a highly potent mutagenic species that reacts with DNA primarily at the N2 atom of a guanine base.
B. The adduct, (+)-trans-anti-B(a)P-N2-dG, causes polymerase to insert an A rather than a C opposite the modified G base. Next time the DNA is replicated, a T will be inserted opposite the A, and the mutation will be complete.
C. Potent mutagen majorly causes conversion of guanine (G) to thymine (T) bases, a transition mutation.
D. When this potent mutagen applied to cultured bronchial epithelial cells, activated benzo(a)pyrene induces many mutations, including activating mutations at codons 175, 248, and 273 of the p53 gene.
Which of the following statements are correct?
#Question id: 3216
#Unit 11. Evolution and Behavior
The frequency of galactosemia is approximately 1 in 40,000 live births. The frequency of the carrier state can be calculated as
#Question id: 31112
#Unit 2. Cellular Organization