In the pedigree shown, on the basis of the linked marker results II 4 can be told that:

TLS Online TPP Program

#Question id: 32407

#Unit 1. Molecules and their Interaction Relevant to Biology

Deuterated acetyl-coenzyme A (-CD3 instead of –CH3) was used in an experiment to study the TCA cycle. Upon analysis of the metabolites, it was found that deuterium (D) was present in a wide variety of compounds; even compounds not associated with the citric acid cycle. This is due to

TLS Online TPP Program

#Question id: 32408

#Unit 1. Molecules and their Interaction Relevant to Biology

What would result if 14CO₂ were incorporated into the TCA cycle via the pyruvate carboxylase reaction.

TLS Online TPP Program

#Question id: 32409

#Unit 1. Molecules and their Interaction Relevant to Biology

What will be the fate if methyl-labeled acetyl-CoA was fed to the conventional TCA cycle.

TLS Online TPP Program

#Question id: 32410

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following statements is false.

a. Pyruvate dehydrogenase is inhibited by NADH.

b. Pyruvate dehydrogenase is inhibited by ATP.

c. Citrate synthase is inhibited by NADH.

d. Succinyl-CoA activates citrate synthase.

e. Acetyl-CoA activates pyruvate carboxylase.

TLS Online TPP Program

#Question id: 32411

#Unit 1. Molecules and their Interaction Relevant to Biology

Activity of citrate synthase from pig heart tissue shows a sigmoid dependence on the concentration of acetyl-CoA. Which of the following statement is correct.

TLS Online TPP Program

#Question id: 5360

#Unit 1. Molecules and their Interaction Relevant to Biology

Following some different genetic disorder traces in families. 

Family	Father	Mother	Son	Daughter
A	Affected	Affected	Unaffected	Unaffected
B	Affected	Affected	Unaffected	Affected
C	Unaffected	Unaffected	Undetermined	Affected
D	Affected	Unaffected	Unaffected	Affected

 Which of the following possible mode of inheritance in the Family A, B, C and D respectively