TLS Online TPP Program

#Question id: 12834


How Aurora B and the spindle assembly checkpoint pathway collaborate during every cell cycle to accurately attach every single pair of sister chromatids to the mitotic spindle in the correct, bioriented manner?

#Unit 2. Cellular Organization
  1. Aurora B phosphorylate microtubule-binding component of the kinetochore, the Ndc80 complex, leads to the generation of attached kinetochores, which are recognized by the spindle assembly checkpoint pathway.
  2. Aurora B phosphorylate microtubule-binding component of the kinetochore, the Ndc80 complex, leads to the generation of unattached kinetochores, which are recognized by the spindle assembly checkpoint pathway.
  3. Aurora B dephosphorylate microtubule-binding component of the kinetochore, the Ndc80 complex, leads to the generation of unattached kinetochores, which are recognized by the spindle assembly checkpoint pathway.
  4. Aurora B ubiquitinylates microtubule-binding component of the kinetochore, the Ndc80 complex, leads to the degradation of unattached kinetochores, which are recognized by the spindle assembly checkpoint pathway.
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TLS Online TPP Program

#Question id: 15334

#Unit 4. Cell Communication and Cell Signaling

In which type of BCR (surface protein) present on to the B-cell, which are responsible for the conversion of membrane bound into secreted form of antibody. If it is not present then this conversion isn’t possible;

TLS Online TPP Program

#Question id: 15335

#Unit 4. Cell Communication and Cell Signaling

Some given following co-receptor present on to the B-cell surface except

TLS Online TPP Program

#Question id: 15336

#Unit 4. Cell Communication and Cell Signaling

Which of the following cell surface markers responsible for the regulation of B-cell ?

TLS Online TPP Program

#Question id: 15337

#Unit 4. Cell Communication and Cell Signaling

HSCs express which type of cell-surface molecule, which is the receptor for stem cell factor (SCF). It is a cytokine that exists in both membrane-bound and soluble forms and the SCF-surface molecules interaction is critical for the development, in adult animals, of multipotential progenitor cells (MPPs).  Which type of surface molecules HSCs express?

TLS Online TPP Program

#Question id: 15338

#Unit 4. Cell Communication and Cell Signaling

Which cell generated on the receipt of SCF/c-Kit signaling lose the capacity for extensive self-renewal, but retain the potential to differentiate into several different hematopoietic lineages and also transiently express the molecule CD34?

TLS Online TPP Program

#Question id: 15339

#Unit 4. Cell Communication and Cell Signaling

HSCs begin their life in close contact with osteoblasts located close to the lining of the endosteal cavity. Once differentiated to the pre-pro-B-cell stage, the developing B cells require Which type of signals from the chemokine, which is secreted by a specialized set of stromal cells?