Practice Questions

TLS Online TPP Program

#Question id: 12834

How Aurora B and the spindle assembly checkpoint pathway collaborate during every cell cycle to accurately attach every single pair of sister chromatids to the mitotic spindle in the correct, bioriented manner?

#Unit 2. Cellular Organization

Aurora B phosphorylate microtubule-binding component of the kinetochore, the Ndc80 complex, leads to the generation of attached kinetochores, which are recognized by the spindle assembly checkpoint pathway.
Aurora B phosphorylate microtubule-binding component of the kinetochore, the Ndc80 complex, leads to the generation of unattached kinetochores, which are recognized by the spindle assembly checkpoint pathway.
Aurora B dephosphorylate microtubule-binding component of the kinetochore, the Ndc80 complex, leads to the generation of unattached kinetochores, which are recognized by the spindle assembly checkpoint pathway.
Aurora B ubiquitinylates microtubule-binding component of the kinetochore, the Ndc80 complex, leads to the degradation of unattached kinetochores, which are recognized by the spindle assembly checkpoint pathway.