What is the main advantage of using Yeast Artificial Chromosome based vector over other vectors?

1. It has ability to clone very large fragments of DNA.

2. YAC vectors do not contain origin of replication sites 

3. It has insert  range up to 2000 kb.

4. It help in genome mapping and sequencing projects.

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#Question id: 19334

#Unit 12. Applied Biology

Which one of the following sensors is also known as mass sensitive biosensor?

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#Question id: 15306

#Unit 4. Cell Communication and Cell Signaling

The transformation of a normal cell to a cancer cell is accompanied  by the loss of function of one or more tumor‐suppressor genes. High‐throughput sequencing studies have identified hundreds of genes that are implicated as tumor suppressors in humans. Some of the better characterized genes;

Gene	Primary tumor	Proposed function
i) APC	Colorectal	Binds β ‐catenin acting as transcription factor
ii) BRCA1	Breast	DNA repair
iii) MSH2, MLH1	Melanoma, pancreatic	p16: Cdk inhibitor ARF: stabilizes p53
iv) E‐Cadherin	Breast, colon	Cell adhesion molecule
v) INK4a	Colorectal	Mismatch repair
vi) NF1	Neurofibromas	Activates GTPase of Ras

Choose incorrect matching regarding tumor‐suppressor genes/primary tumor/proposed functions;

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#Question id: 10932

#Unit 7. System Physiology – Animal

A 62-year-old man complains of headaches, visual difficulties, and chest pains. His examination shows a red complexion and a large spleen. His complete blood count follows: hematocrit, 58%, WBC 13,300/μl, and platelets 600,000/μl. His arterial oxygen saturation is 97% on room air. Which of the following would you recommend as a treatment?

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#Question id: 5005

#Unit 11. Evolution and Behavior

Fossilized stromatolites

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#Question id: 15990

#Unit 12. Applied Biology

 Several given biological method involve in the plant transformation, except?