A 55-year-old male patient with hypertension has had his blood pressure reasonably well controlled by administration of a thiazide diuretic. During his last visit (6 months ago) his blood pressure was 130/75 mm Hg and his serum creatinine was 1 mg/100 ml. He has been exercising regularly for the past 2 years, but recently has complained of knee pain and began taking large amounts of a nonsteroidal anti-inflammatory drug. When he arrives at your office, his blood pressure is 155/85 and his serum creatinine is now 2.5 mg/100 ml. Which of the following best explains his increased serum creatinine?

#Question id: 5122

#Unit 5. Developmental Biology

In amphibia, when epidermal (ectodermal) and mesodermal cells are brought together in a mixed aggregate, the epidermal cells move to the periphery of the aggregate, and the mesodermal cells move to the inside by the process of selective affinity. Which of the following statement describe the phenomena of selective affinity?

#Question id: 5123

#Unit 5. Developmental Biology

The generation of specialized cell typces is called ‘differentiation’, a process during which-

#Question id: 5124

#Unit 5. Developmental Biology

Following statements are being made regarding conditional specification –

A. The process by which cells achieve their respective fates by interacting with other cells.

B. the cell “knows” very early what it is to become without interacting with other cells.

C. The critical factors that control cell fate are present and differentially segregated in the cytoplasm of these cells.

D. a cell becomes is specified by the array of interactions it has with its neighbors, which may include cell-to-cell contacts (juxtacrine factors), secreted signals (paracrine factors).

Which of the above statements are correct?

#Question id: 5125

#Unit 5. Developmental Biology

In above experiment in figure.A two differently positioned blastula cells are specified to become distinct muscle and neuronal cells.In figure.B when These two different blastula cells are placed together in culture. Following results are obtained according to step(1) and step(2). Which statement is correct about muscle cell commitment?

#Question id: 5126

#Unit 5. Developmental Biology

Which one is correct according to adult stem cell lineage?

#Question id: 5127

#Unit 5. Developmental Biology

The following are certain statements regarding stem cells. Which one is correct?