#Question id: 4256
#Unit 2. Cellular Organization
With respect to CpG islands in our genomic DNA, which, if any, of the following descriptions do not apply?
1) frequently occurring (there are about 30,000 in the human genome).
2) long DNA sequences (typically from 10 kb to 100 kb in length).
3) low CG dinucleotide frequency.
4) frequently associated with transcriptional start sites.
#Question id: 4257
#Unit 3. Fundamental Processes
An original section of DNA has the base sequence AGCGTTACCGT. A mutation in this DNA strand results in the base sequence AGGCGTTACCGT. What type of mutation does this change represent?
#Question id: 4258
#Unit 3. Fundamental Processes
A single base substitution mutation is likely to have a less deleterious effect when the base change exhibits which of the following results?
#Question id: 4259
#Unit 3. Fundamental Processes
Rank the following one-base point mutations with respect to their likelihood of affecting the structure of the corresponding polypeptide (from most likely to least likely).
1. insertion mutation deep within an intron
2. substitution mutation at the third position of a codon in an exon
3. substitution mutation at the second position of a codon in an exon
4. deletion mutation within the first exon of the gene
#Question id: 4260
#Unit 3. Fundamental Processes
Which of the following occur(s) when the eukaryotic translational machinery encounters the TAG codon?
#Question id: 4261
#Unit 3. Fundamental Processes
Polyadenylation can promote translation
a. of the fragile-X gene.
b. of stored oocyte mRNAs.
c. by allowing for greater interaction at the 5´ end.
d. by allowing for greater interaction with translation initiation factors.