Biologists performed an experiment with flies to examine the effects of population size on the maintenance of genetic variation  and  on  egg-to-adult survival.  From  a  large  source  population, they  randomly  assigned  eggs  to  three experimental  populations  of  size  N,  equal  to  20,  60,  and0100.  For  later  generations,  they  collected  N  eggs  from each  population  and  moved  them  into  identical  vials  that  co0ntained  f2re0sh  me4d0ium.  Th6e0y  coun8te0d  the  number  of adult flies that emerged and used tissue samples from the adults for genetic analyses. Genetic variation was measured by  scoring  alleles  at  several  polymorphic  loci  and  expressed  as  the  average  number  of  alleles  at  those  loci.  The results are summarized in Figure 1 and Figure 2 below.

Based on Figure 1, which of the following best describes the change in genetic variation over time? 

TLS Online TPP Program

#Question id: 33982

#Unit 2. Cellular Organization

A. Chromosomes occupy chromosome territories in the nucleus and very much entangled with each other. 

B. Heterochromatic regions, silenced genes, and gene-sparse regions of chromosomes are typically localized to the nuclear periphery and center of nucleus. 

C. Active genes are often found at the borders and of chromosome territories

D. Active genes from several chromosomes may cluster in inter-chromosomal territories that are enriched in transcription machinery

Choose true and false

TLS Online TPP Program

#Question id: 33983

#Unit 2. Cellular Organization

Which of the protein hold heterochromatin region attached to nuclear wall

TLS Online TPP Program

#Question id: 33984

#Unit 2. Cellular Organization

Choose correct combination of statements 

A. Each chromosome contains many fragments of very long duplex of DNA, folded into a fiber that runs continuously throughout the chromosome.

B. During interphase, euchromatin, which is slightly densely packed than mitotic chromosomes. 

C. Regions of heterochromatin remain densely packed throughout interphase.

D. Various heterochromatic regions, especially those associated with centromeres, aggregate into a densely staining chromocenter

TLS Online TPP Program

#Question id: 33985

#Unit 2. Cellular Organization

To analyze existing MARs that are bound to the matrix in vivo, what is correct order of method 

A. Chromosomal loops decondensed by extracting the chromatin proteins. 

B. Removal of the DNA loops by treatment with restriction nucleases

C. Amplification of MAR and sequencing

TLS Online TPP Program

#Question id: 33986

#Unit 2. Cellular Organization

What is the relationship between the chromosome scaffold of dividing cells and the matrix of interphase cells

A. The same DNA fragments that are found within the nuclear matrix in vivo can be retrieved from the metaphase scaffold

B. Fragments containing MAR sequences can bind to a metaphase scaffold; it is likely that DNA contains a single type of attachment site.

C. In interphase cells the attachment site is connected to the nuclear matrix, whereas in mitotic cells it is connected to the chromosome scaffold.

TLS Online TPP Program

#Question id: 34086

#Unit 3. Fundamental Processes

Replicators/replicons can be identified using a