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#Question id: 797
#Part-B Specialized Branches in Biotechnology
With respect to microRNAs, which, if any, of the following statements, is FALSE?)
A. MicroRNA genes often occur in gene clusters within introns of protein-coding genes and are usually transcribed by RNA polymerase II.
B. Like an mRNA a miRNA is initially produced as a larger precursor RNA that, like the great majority of mRNAs, usually has a 5’ cap and a poly(A) tail.
C. MicroRNAs are produced by germ-line cells only.
D. A miRNA is initially produced as a duplex RNA but in order to work it needs to be converted into a single-strand RNA.
E. MicroRNAs usually work as transcription factors.
#Question id: 799
#Part-B Specialized Branches in Biotechnology
The two cleavage reactions required to generate the miRNA from these primary transcripts are mediated by two distinct RNases. A characteristic of both these enzymes is that they recognize and cleave RNAs on the basis of the structure of their substrates rather than their specific sequence. Which of the following statement is INCORRECT regarding the cleavage reactions that produces a mature RNA?